What are the Diagnostic Biomarkers in Psychiatry?

A biomarker attempts to use biological information like proteins in blood, brain waves, or genetics to gather information about a psychiatric condition. This can be information on whether or not someone has a psychiatric illness, if they will develop an illness in the future, or what kinds of therapy they might respond to. These kinds of tests are used frequently for other medical conditions, but it has been difficult to find good tests for use in psychiatric illness. Below are some of the current biomarkers available for clinical use for psychiatric illness.

DIAGNOSTIC BIOMARKERS
This measures if the someone has a disease

MDDScore
blood test to diagnose major depressive disorder
measures levels of 9 proteins a blood sample
recommended for use in conjunction with clinical evaluation
approx cost $825

VeriPsych
blood test to diagnose schizophrenia
measures levels of 51 proteins in a blood sample
recommended for use in conjunction with clinical evaluation
approx cost $2500 when available, currently not available

NEBA
brain waves to diagnose attention deficit hyperactivity disorder (ADHD)
measures EEG ratio of theta to beta brain waves
recommended for use in conjunction with clinical evaluation
cost $325

PROGNOSTIC BIOMARKERS
This measures if someone will develop a disease

THERANOSTIC (PREDICTIVE) BIOMARKERS
This measures whether a patient will respond to a particular therapy

ATR score
for use in depression
to predict response to particular antidepressants
uses quantitative EEG
not available yet

GENESIGHT
genetic test to predict side effects and dosing of different medications based on patient genotype
uses check swab
cost $3800 but insurance will sometimes cover most of the cost

If you have any questions or want more advice about taking one of these tests, please do not hesitate to reach out to us. 919-636-5240 or email us at office@cognitive-psychiatry.com

Live Mentally Healthy,
Dr. Jennie Byrne

Author
Dr. Jennie Byrne, M.D., PhD. With over 15 years of medical expertise, Jennie Byrne, MD, PhD, is a board-certified psychiatrist with experience treating mental health conditions in adults, including dementia, attention-deficit hyperactivity disorder, anxiety, and depression. After practicing in New York City for 12 years, Dr. Byrne relocated to North Carolina in 2008; she currently cares for patients in Chapel Hill, North Carolina, at Cognitive Psychiatry of Chapel Hill. Dr. Byrne earned her bachelor’s degree at the University of Pennsylvania in Philadelphia. She then received her doctorate from New York University Department of Neurophysiology. She also has a doctorate of medicine from New York University School of Medicine. Dr. Byrne went on to complete a psychiatry residency at Mt. Sinai School of Medicine in New York. In addition to her work as a psychiatrist, Dr. Byrne has performed extensive research on attention, memory, and depression. As a board-certified adult psychiatrist, Dr. Byrne focuses on the needs of each patient to pro

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